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Recombinant Human LAMP1/CD107a (C-6His)

Recombinant Human LAMP1/CD107a (C-6His)

SKU: C482-10ug
$84.00Price
Recombinant Human LAMP1 is produced by our Mammalian expression system and the target gene encoding Ala29-Met382 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #C482
Endotoxin
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Accession Number
P11279
Species
Human
Expression System
Human Cells
Target Sequence
Ala29-Met382
Tag
C-His
Formulation
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Packaging
Ambient
Background
Lysosome-Associated Membrane Glycoprotein 1 (LAMP1) is a single-pass type I membrane protein belonging to the LAMP family. LAMP1 is expressed largely in the endosome-lysosome membranes of cells.It shuttles between lysosomes, endosomes, and the plasma membrane. LAMP1 functions to present carbohydrate ligands to selectins and it has also been implicated in tumor cell metastasis. It has been proposed LAMP1 can be used as a therapeutic agent for certain cancers, as well as a marker for lysosomal storage disorders and degranulation on lymphocytes such as CD8+ and NK cells. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells(PBMC) to vascular endothelium, therefore they are possibly involved in the adhesion of PBMCs to the site of inflammation.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Lysosome-Associated Membrane Glycoprotein 1; LAMP-1; Lysosome-Associated Membrane Protein 1; CD107 Antigen-Like Family Member A; CD107a; LAMP1
Alternative Names
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Citation
NA
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