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Recombinant Human Isocitrate Dehydrogenase 1/IDH1 (R132H, C-8His)
Recombinant Human Isocitrate Dehydrogenase is produced by our E.coli expression system and the target gene encoding Met1-Leu414 is expressed with a 8His tag at the C-terminus. Bon Opus Cat. #CM34

Recombinant Human Isocitrate Dehydrogenase 1/IDH1 (R132H, C-8His)

SKU: CM34-10ug
$158.00Price
Quantity
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$48 Standard Overnight flat rate for products shipped in room temperature within the United States.

 

Additional $27 Ice Packs shipment fee is required for liquid proteins.

 

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Endotoxin
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Accession Number
O75874
Species
Human
Expression System
E.coli
Target Sequence
Met1-Leu414
Tag
N-His
Formulation
Supplied as a 0.2 um filtered solution of 50mM Tris-HCl, 200mM NaCl, 10% Glycerol, pH 8.0.
Packaging
Dry Ice/Polar Packs
Background
Isocitrate Dehydrogenase [NADP] Cytoplasmic (IDH1) belongs to the isocitrate and isopropylmalate dehydrogenases family. IDH1 exists as a homodimer, binding one magnesium or manganese ion per subunit. Mutations of IDH1 have been shown to cause metaphyseal chondromatosis with aciduria and are involved in the development of glioma. IDH plays a role in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the α-hydroxylation of phytanic acid.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Isocitrate Dehydrogenase [NADP] Cytoplasmic; IDH; Cytosolic NADP-Isocitrate Dehydrogenase; IDP; NADP(+)-Specific ICDH; Oxalosuccinate Decarboxylase; IDH1; PICD
Alternative Names
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Citation
NA
Activity
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