Recombinant Human Interleukin-18 is produced by our E.coli expression system and the target gene encoding Tyr37-Asp193 is expressed. Bon Opus Cat. #CH29 (BP072)
Recombinant Human Interleukin-18/IL-18/IL-1F4
SKU: CH29-10ug
$110.00Price
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Shipping Information
$48 Standard Overnight flat rate for products shipped in room temperature within the United States.
Additional $27 Ice Packs shipment fee is required for liquid proteins.
Please contact us to order for international shipments.
Endotoxin
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Accession Number
Q14116
Species
Human
Expression System
E.coli
Target Sequence
Tyr37-Asp193
Tag
tag free
Formulation
Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Packaging
Ambient
Background
Interleukin-18 is a secreted protein and it belongs to the IL-1 family. IL-18 is a proinflammatory cytokine and produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL-4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. After stimulation with IL-18, natural killer (NK) cells and certain T cells release another important cytokine called interferon-γ (IFN-γ) or type II interferon that plays an important role in activating the macrophages or other cells.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Interleukin-18; Iboctadekin; Interferon gamma-inducing factor; IFN-gamma-inducing factor; Interleukin-1 gamma; IL-1 gamma;GIF; IL-18; IL-1g; IL1F4; MGC12320
Alternative Names
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Citation
NA
Activity
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