Recombinant Human Interleukin-18/IL-18

Recombinant Human Interleukin-18/IL-18

SKU: BP072-50ug
Recombinant Human IL-18 is produced by E.coli. The target gene encoding Tyr37-Asp193 is expressed.
  • Accession Number

  • Expression

  • Background

    Interleukin-18 (IL-18) is a secreted protein that belongs to the IL-1family. IL-18 is a proinflammatory cytokine and can be expressed by multiple types of cells, including endothelial and epithelial cells, keratinocytes, gamma delta T cells, and phagocytes. This cytokine can modulate both innate and adaptive. Once binding to IL18R1 and IL18RAP, it can form a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. The combination of IL-18 and IL-12 can induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells.
  • Formulation

    Lyophilized frum a 0.2 um filtered solution of PBS, pH7.4
  • Packaging

  • ALTnames

    Interleukin-18; Iboctadekin; Interferon gamma-inducing factor; IFN-gamma-inducing factor;Interleukin-1 gamma; IL-1 gamma;GIF; IL-18; IL-1g; IL1F4; MGC12320
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