Recombinant Human Interferon γ Receptor 1/IFNGR1 (C-6His)
Recombinant Human Interferon gamma receptor 1 is produced by our Mammalian expression system and the target gene encoding Glu18-Ser245 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #CI70
BackgroundInterferon gamma receptor 1(IFNGR1) encoded by the IFNGR1 gene, is a single-pass type 1 membrane protein which belongs to the type II cytokine receptor family. IFNGR1 is phosphorylated at Ser/Thr residues after translation. IFNGR1 is a receptor for interferon gamma, two receptors bind one interferon gama dimer. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.
PackagingDry Ice/ice packs
FormulationSupplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
ALTnamesInterferon gamma receptor 1,IFNGR1,CDw119,CD119