Recombinant Human Insulin-Like Growth Factor I/IGF-I/IGF1 (4-70)

Recombinant Human Insulin-Like Growth Factor I/IGF-I/IGF1 (4-70)

SKU: C031-10ug
Recombinant Human Insulin-like Growth Factor I is produced by our E.coli expression system and the target gene encoding Thr52-Ala118 is expressed. Bon Opus Cat. #C031
  • Accession Number

  • Background

    Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGFs are generated by proteolytic processing of inactive precursor protein containing N-terminal and C-terminal propeptide regions. Mature human IGF-I consisting of 70 amino acids with 94% identity with mouse IGF1 and exhibits cross-species activity. IGF1 binds IGF-1R, IGF-2R, and the insulin receptor and plays a key role in cell cycle progression, cell proliferation and tumor progression. IGF1 expression is regulated by growth hormone.
  • Expression

    E. coli
  • Packaging

  • Formulation

    Lyophilized from a 0.2 μm filtered solution of 300mM NaAc, pH 6.5.
  • ALTnames

    Insulin-Like Growth Factor I, IGF-I, Mechano Growth Factor, MGF, Somatomedin-C, IGF1, IBP1

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