Recombinant Human IL-18 Receptor Accessory Protein/IL-18RAcP/IL-1R7 (C-6His)
Recombinant Human IL-18RAcP is produced by our Mammalian expression system and the target gene encoding Phe20-Arg356 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #CB73
BackgroundIL-18RAP is a single-pass type I membrane protein and contains two Ig-like C2-type domains and one TIR domain, IL18RAP can be induced by IFN-alpha and IL12 in nature killer cells and T-cells. The coexpression of IL18R1 and IL18RAP is required for the activation of NF-kappa B and JNK in response to IL-18.Defects in IL18RAP are associated with Coeliac disease.
FormulationLyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
ALTnamesInterleukin-18 receptor accessory protein (IL18RAP), Accessory protein-like, CD218 antigen-like family member B, CDw218b, IL-1R accessory protein-like, Interleukin-1 receptor 7, Interleukin-18 receptor accessory protein-like, Interleukin-18 receptor beta￡¨CD218b and IL1R7.