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Recombinant Human Glutathione Synthetase/GSH Synthetase (C-6His)

SKU: CE58-10ug
$150.00Price
Recombinant Human GSH Synthetase is produced by our E.coli expression system and the target gene encoding Ala2-Val474 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #CE58
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  • Accession Number

    P48637

  • Background

    Glutathione Synthetase belongs to the eukaryotic GSH synthase family. Glutathione Synthetase is the second enzyme in the glutathione biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine and glycine to form glutathione. Glutathione play an important role in a variety of biological functions, including detoxification of xenobiotics, protection of cells from oxidative damage by free radicals, and membrane transport. The protein functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in Glutathione Synthetase can also cause the glutathione synthetase deficiency of erythrocytes, which is a mild form causing hemolytic anemia.

  • Expression

    E. coli

  • Packaging

    Dry ice/Polar packs

  • Formulation

    Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 200mM NaCl, pH 7.5 .

  • ALTnames

    Glutathione Synthetase, GSH Synthetase, GSH-S, Glutathione Synthase, GSS