Recombinant Human Glia Maturation Factor β/GMF-β/GMFB (C-6His)
Recombinant Human Glia maturation factor beta is produced by our E.coli expression system and the target gene encoding Met1-His142 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #CH77
BackgroundGlia maturation factor beta (GMFB) contains a ADF-H domain，which is a member of the actin-binding proteins ADF family, GMF subfamily. It is a nerve growth factor implicated in nervous system development, angiogenesis and immune function. GMFB causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells. It is phosphorylated after phorbol ester stimulation, and is crucial for the nervous system. GMFB overexpression in astrocytes results in the increase of BDNF production. GMFB expression is increased by exercise, thus BDNF is important for exercise-induction of BDNF.
FormulationLyophilized from a 0.2 μm filtered solution of 20mM Tris,200mMNaCl,pH8.0.
ALTnamesGlia maturation factor beta，GMF-beta, GMFB