Recombinant Human Galectin 9 (C-6His)
Recombinant Human Galectin 9 is produced by our Mammalian expression system and the target gene encoding Met1-Thr323 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #C808
BackgroundGalectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin's disease tissue. Galectin-9 binds galactosides and has high affinity for the Forssman pentasaccharide. Galectin-9 plays a role in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. Galectin-9 is a ligand for HAVCR2/TIM3 and induces T-helper type 1 lymphocyte (Th1) death. In addition, Galectin-9 suppresses tumor cell metastasis by interfering with the associations CD44, VCAM-1, Integrin α4β1.
FormulationLyophilized from a 0.2 μm filtered solution of PBS,5% Trehalose,1mM EDTA,pH7.4.
ALTnamesGalectin-9; Gal-9; Ecalectin; Tumor Antigen HOM-HD-21; LGALS9