Recombinant Human Fibroblast growth factor 19 is produced by our E.coli expression system and the target gene encoding Phe27-Lys216 is expressed with a 6His tag at the N-terminus. Bon Opus Cat. #CG74

Recombinant Human Fibroblast Growth Factor 19/FGF-19 (N-6His)

Name: Recombinant Human Fibroblast Growth Factor 19/FGF-19 (N-6His)
SKU: CG74-10ug

SKU: CG74-10ug

$110.00

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Quantity

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Phone: 800-943-6396 ext#1

Email: orders@bonopusbio.com

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Shipping Information

$48 Standard Overnight flat rate for products shipped in room temperature within the United States.

Additional $27 Ice Packs shipment fee is required for liquid proteins.

Please contact us to order for international shipments.

Certificate of Analysis

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Endotoxin

Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.

Accession Number

O95750

Species

Human

Expression System

E.coli

Target Sequence

Phe27-Lys216

N-His

Formulation

Lyophilized from a 0.2 um filtered solution of 20mMTris-HCl,150mMNaCl,1mMEDTA,pH8.0.

Packaging

Ambient

Background

Fibroblast growth factor 19 (FGF19) is a secreted protein which belongs to the FGFs family. FGF19 is expressed in fetal brain, cartilage, retina, and adult gall bladder. FGFs modulate cellular activity via at least 5 distinct subfamilies of high-affinity FGF receptors (FGFRs): FGFR-1, -2, -3, and -4, all with intrinsic tyrosine kinase activity. FGFRs can be important for regulation of glucose and lipid homeostasis. FGF19 has important roles as a hormone produced in the ileum in response to bile acid absorption. It has been shown to cause resistance to diet-induced obesity and insulin desensitization and to improve insulin, glucose, and lipid profiles in diabetic rodents. FGF19 can be considered as a regulator of energy expenditure.