Recombinant Human Fibroblast Growth Factor 19/FGF-19 (N-6His)
SKU: CG74-10ug
$105.00Price
Recombinant Human Fibroblast growth factor 19 is produced by our E.coli expression system and the target gene encoding Phe27-Lys216 is expressed with a 6His tag at the N-terminus. Bon Opus Cat. #CG74
Size
Accession Number
O95750Background
Fibroblast growth factor 19 (FGF19) is a secreted protein which belongs to the FGFs family. FGF19 is expressed in fetal brain, cartilage, retina, and adult gall bladder. FGFs modulate cellular activity via at least 5 distinct subfamilies of high-affinity FGF receptors (FGFRs): FGFR-1, -2, -3, and -4, all with intrinsic tyrosine kinase activity. FGFRs can be important for regulation of glucose and lipid homeostasis. FGF19 has important roles as a hormone produced in the ileum in response to bile acid absorption. It has been shown to cause resistance to diet-induced obesity and insulin desensitization and to improve insulin, glucose, and lipid profiles in diabetic rodents. FGF19 can be considered as a regulator of energy expenditure.Expression
E. coliPackaging
AmbientFormulation
Lyophilized from a 0.2 μm filtered solution of 20mM PB，150mM NaCl,pH7.4.ALTnames
Fibroblast growth factor 19, FGF-19, FGF19