Recombinant Human IgG Fc fragment receptor transporter is produced by our Mammalian expression system and the target gene encoding Ala24-Leu290&Ile21-Met119 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #CI01

Recombinant Human FcRn & B2M Heterodimer (C-6His)

Name: Recombinant Human FcRn & B2M Heterodimer (C-6His)
SKU: CI01-10ug

SKU: CI01-10ug

$110.00

Quantity

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Shipping Information

$48 Standard Overnight flat rate for products shipped in room temperature within the United States.

Additional $27 Ice Packs shipment fee is required for liquid proteins.

Please contact us to order for international shipments.

Certificate of Analysis

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Endotoxin

Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.

Accession Number

AAF72596&P61769

Species

Human

Expression System

Human Cells

Target Sequence

Ala24-Leu290&Ile21-Met119

C-His

Formulation

Lyophilized from a 0.2 um filtered solution of 50mM HEPES, 150mM Nacl, pH 7.4.

Packaging

Ambient

Background

FcRn complex consist of two subunits: IgG receptor FcRn large subunit p51（alpha chain) and Beta-2-microglobulin（Beta chain). The complexes is similar in structure to MHC class I-like heterodimer. Beta-2-microglobulin involved in the presentation of peptide antigens to the immune system. FcRn binds to the Fc region of monomeric immunoglobulins gamma, mediates the uptake of IgG from milk,Possible role in transfer of immunoglobulin G from mother to fetus. A principal component of antibody transport is the neonatal receptor for the Fc portion of immunoglobulin, a heterodimer of a MHC-1 alpha-chain homolog ( FcRn ) and beta-2-microglobulin ( B2M ).