BackgroundEukaryotic Translation Initiation Factor 1B (EIF1B) is an element of a complex involved in recognition of the initiator codon during the scanning process. Translation is also initiated by the function of EIF1B in regulating the activity of ribosomal subunits 43S, 48S and 40S. EIF1B enables 43S ribosomal complexes to distinguish between cognate and near-cognate initiation codons, perceiving the nucleotide content of initiation codons.
FormulationLyophilized from a 0.2 μm filtered solution of 20mM TrisHCl, 500mM NaCl, pH 8.0.
ALTnamesEukaryotic Translation Initiation Factor 1b, eIF1b, Protein Translation Factor SUI1 Homolog GC20, EIF1B