Recombinant Human ER alpha (N-His)

Recombinant Human ER alpha (N-His)

SKU: BP157-10ug
Recombinant Human Estrogen receptor alpha is produced by our E.coli expression system and the target gene encoding Met1-Gln116 is expressed with a 6His tag at the N-terminus.
  • Accession Number

  • Expression

  • Background

    Estrogen Receptor is a major ligand-activated transcription factor that belongs to the nuclear hormone receptor superfamily. It is widely expressed and acts as a strong activator of estrogen-responsive genes. Estrogen Receptor is composed of several domains essential for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are necessary for sexual development and reproductive function, but they also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis.
  • Formulation

    Supplied as a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
  • Packaging

    Dry ice/ice pack
  • ALTnames

    Estrogen Receptor; ER; ER-Alpha; Estradiol Receptor; Nuclear Receptor Subfamily 3 Group A Member 1; ESR1; ESR; NR3A1
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