BackgroundSELE is expressed on the surface of endothelial cells and mediates the interaction of leukocytes and platelets with endothelial cells during an inflammatory response. SELE functions as a cell-surface glycoprotein and has a role in immunoadhesion. In addition, SELE may also have a role in capillary morphogenesis.
FormulationLyophilized from a 0.2 μm filtered solution of PBS, 4% Mannitol,pH7.4.
ALTnamesE-selectin (SELE), also known as CD62 antigen-like family member E, Endothelial leukocyte adhesion molecule 1, Leukocyte-endothelial cell adhesion molecule 2, CD62E and ELAM1, is a single-pass type I membrane protein which belongs to the selectin/LECAM family.