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Recombinant Human DNA Fragmentation Factor Subunit α/DFFA/DFF45/ICAD (N-6His)
Recombinant Human DFF45 is produced by our E.coli expression system and the target gene encoding Met1-Thr331 is expressed with a 6His tag at the N-terminus. Bon Opus Cat. #CE91

Recombinant Human DNA Fragmentation Factor Subunit α/DFFA/DFF45/ICAD (N-6His)

SKU: CE91-10ug
$100.00Price
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$48 Standard Overnight flat rate for products shipped in room temperature within the United States.

 

Additional $27 Ice Packs shipment fee is required for liquid proteins.

 

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Endotoxin
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Accession Number
AAH07721.1
Species
Human
Expression System
E.coli
Target Sequence
Met1-Thr331
Tag
N-His
Formulation
Supplied as a 0.2 um filtered solution of PBS, pH 7.4.
Packaging
Dry ice/Polar packs
Background
DNA Fragmentation Factor Subunit Alpha (DFFA). DFFA exists as a heterodimer (DFF) with DFFB. DFF is activated once DFFA is cleaved by Caspase-3. The cleaved fragments of DFFA detach from DFFB (the active component of DFF), which in turn triggers DNA fragmentation as well as chromatin condensation during apoptosis. A reduced level of DFFA detected in ovarian endometriosis may be a part of an apoptosis-resistant mechanism enhancing the disease progression.
Purity
Greater than 85% as determined by reducing SDS-PAGE.
DNA Fragmentation Factor Subunit Alpha; DNA Fragmentation Factor 45 kDa Subunit; DFF-45; Inhibitor of CAD; ICAD; DFFA; DFF1; DFF45; H13
Alternative Names
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Citation
NA
Activity
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