Recombinant Human Death Domain-Containing Protein CRADD/CRADD

Name: Recombinant Human Death Domain-Containing Protein CRADD/CRADD
Brand: Bon Opus Biosciences
SKU: CF64-10ug

SKU: CF64-10ug

$150.00

Recombinant Human CRADD/ is produced by our E.coli expression system and the target gene encoding Met1-Glu199 is expressed. Bon Opus Cat. #CF64

Size

Quantity

Accession Number
P78560
Background
Death Domain-Containing Protein CRADD (CRADD) is widely expressed in most tissues, with particularly high expression in the adult heart, testis, liver, skeletal muscle, fetal liver, and kidney. CRADD contains one CARD domain that mediates the interaction with caspase-2, and one death domain involved in the binding of RIP protein. CRADD functions as an apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. CRADD induces cell apoptosis/cell death in numerous tissues. Defects in CRADD will result in mental retardation.
Expression
E. coli
Packaging
Ambient
Formulation
Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
ALTnames
Death Domain-Containing Protein CRADD, Caspase and RIP Adapter with Death Domain, RIP-Associated Protein with A Death Domain, CRADD, RAIDD