Recombinant Human D-Tyrosyl-tRNA(Tyr) Deacylase 1/DTD1 (C-6His)
Recombinant Human DTD1 is produced by our Mammalian expression system and the target gene encoding Met1-Pro209 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #CI72
BackgroundD-tyrosyl-tRNA(Tyr) deacylase 1(DTD1) belongs to the DTD family, and expressed in many adult and fetal tissues such as testis, ovary, spleen in adult and fetal brain. It is a nucleus and cytoplasm located protein, and is preferentially phosphorylated in cells arrested early in S phase. DTD1 is an ATPase involved in DNA replication, it may facilitate loading of CDC45 onto pre-replication complexes. The protein may hydrolyze D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr), a possible defense mechanism against a harmful effect of D-tyrosine.
PackagingDry ice/Polar packs
FormulationSupplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
ALTnamesD-tyrosyl-tRNA(Tyr) deacylase 1,DNA-unwinding element-binding protein B,DUE-B,Histidyl-tRNA synthase-related,DTD1,C20orf88, DUEB, HARS2