Recombinant Human Collagen α-1(IX) Chain/COL9A1 (C-6His)
Recombinant Human COL9A1 is produced by our Mammalian expression system and the target gene encoding Ala24-Pro328 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #CI29
BackgroundCOL9A1, which is short for Collagen alpha-1(IX) chain, is a 921 aa. protein. It is a secreted protein, and exists in extracellular space and extracellular matrix. This protein is a heterotrimer of an alpha 1(IX), an alpha 2(IX) and an alpha 3(IX) chain.Each subunit is composed of three triple-helical domains interspersed with non-collagenous domains. The globular domain at the N-terminus of type IX collagen molecules represents the NC4 domain which may participate in electrostatic interactions with polyanionic glycosaminoglycans in cartilage. It ia a structural component of hyaline cartilage and vitreous of the eye.
FormulationLyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl, pH7.4.
ALTnamesCollagen alpha-1(IX) chain,DJ149L1.1.2; EDM6; MED; STL4