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Recombinant Human CEACAM5 is produced by our Mammalian expression system and the target gene encoding Lys35-Ala685 is expressed with a Fc tag at the C-terminus. Bon Opus Cat. #CP16

Recombinant Human CEACAM5/CD66e/CEA (C-Fc)

SKU: CP16-10ug
$100.00Price
Quantity
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Endotoxin
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Accession Number
NP_004354.3
Species
Human
Expression System
Human Cells
Target Sequence
Lys35-Ala685
Tag
C-Fc
Formulation
Lyophilized from a 0.2 um filtered solution of 20mMPB,150mMNaCl,pH7.2.
Packaging
Ambient
Background
Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) belong to a group of mammalian immunoglobulin related glycoproteins. They play critical roles in cell–cell recognition. CEACAM5, also called CEA and CD66e, is characterized by having seven extracellular Ig domains and a glycosylphosphatidylinositol (GPI) anchor. CEACAM5 is expressed primarily by epithelial cells, and functions as a calcium-independent adhesion molecule through homophilic and heterophilic interactions with CEACAM1. Studies have shown that CEACAM5 is overexpressed in a majority of carcinomas, and its overexpression can protect tumor cells from apoptosis. It is commonly used as a cancer marker.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Carcinoembryonic antigen-related cell adhesion molecule 5; CEACAM5; Carcinoembryonic antigen; CEA; Meconium antigen 100; CD66e
Alternative Names
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Citation
NA
Activity
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