Recombinant Human Basigin is produced by our Mammalian expression system and the target gene encoding Ala22-His205 is expressed with a mFc tag at the C-terminus.
Recombinant Human CD147 (C-mFc)
SKU: C10C-10ug
$54.00Price
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Shipping Information
$48 Standard Overnight flat rate for products shipped in room temperature within the United States.
Additional $27 Ice Packs shipment fee is required for liquid proteins.
Please contact us to order for international shipments.
Endotoxin
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Accession Number
P35613-2
Species
Human
Expression System
Human Cells
Target Sequence
Ala22-His205
Tag
C-mFc
Formulation
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Packaging
Ambient
Background
Basigin/CD147 is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermatogenesis, embryo implantation, neural network formation. CD147 induces the production and release of matrix metalloproteinases (MMP) in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Furthermore, CD147 also serves as a receptor for extracellular cyclophilinthe and its association with integrins might be important in signal transduction. CD147 displays increased expression in many cancers, and it has been previously demonstrated to participate in cancer metastasis and progression.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Basigin; Basic immunoglobulin superfamily; HT7 antigen; Membrane glycoprotein gp42; CD147; Bsg
Alternative Names
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Citation
NA
Activity
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