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Recombinant Human Carbonic Anhydrase 1/CA1 (C-6His)

Recombinant Human Carbonic Anhydrase 1/CA1 (C-6His)

SKU: C107-10ug
$63.00Price
Recombinant Human Carbonic Anhydrase 1 is produced by our E.coli expression system and the target gene encoding Ala2-Phe261 is expressed with a 6His tag at the C-terminus.
Endotoxin
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Accession Number
P00915
Species
Human
Expression System
E.coli
Target Sequence
Ala2-Phe261
Tag
C-His
Formulation
Supplied as a 0.2 um filtered solution of 12.5mM Tris HCl,75mM NaCl,pH 7.5.
Packaging
Dry ice/ice packs
Background
Carbonic Anhydrase 1 (CA1) is a cytosolic enzyme, belonging to the alpha-carbonic anhydrase family. It is highly expressed in erythrocytes and acts as an early marker for erythroid differentiation. Carbonic anhydrase 1 plays a improtant role in many biological processes such as calcification, cellular respiration, bone resorption, acid-base balance. It is activated by imidazole, histamine, L-adrenaline, L- and D-histidine, and L- and D-phenylalanine. At the same time, It is inhibited by sulfonamide derivatives and coumarins. In addition, CA1 is a zinc metalloenzyme that has reversible hydration of carbon dioxide. It can hydrate cyanamide to urea.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Carbonic Anhydrase 1; Carbonate Dehydratase I; Carbonic Anhydrase B; CAB; Carbonic Anhydrase I; CA-I; CA1
Alternative Names
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Citation
Measured by its esterase activity.
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