Recombinant Human CaM Kinase I/CAMK1 (C-6His)
Recombinant Human CaM Kinase I is produced by our Mammalian expression system and the target gene encoding Met1-Leu370 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #C937
BackgroundCalcium/Calmodulin-Dependent Protein Kinase Type 1 (CAMK1) belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family, and CaMK subfamily. CAMK1 contains one protein kinase domain and widely expressed. CAMK1 is phosphorylated by CaMKK1 and CaMKK2 on Thr-177. CAMK1 regulates transcription activators activity, cell cycle, hormone production, cell differentiation, actin filament organization, and neurite outgrowth. CAMK1 plays a role in K+ and ANG2-mediated regulation of the aldosterone synthase (CYP11B2) to produce aldosterone in the adrenal cortex.
FormulationLyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
ALTnamesCalcium/Calmodulin-Dependent Protein Kinase Type 1, CaM Kinase I, CaM-KI, CaM Kinase I Alpha, CaMKI-Alpha, CAMK1