BackgroundHuman Chemokine (C-C Motif) Ligand 27 (CCL27) is a small cytokine that is a member of the CC chemokine family; it is expressed in numerous tissues, including gonads, thymus, placenta and skin. CCL27 elicits its chemotactic effects by binding to the chemokine receptor CCR10. Predominantly expressed in the skin, CCL27 is associated with T cell-mediated inflammation of the skin. Human and Mouse CCL27 share 84% sequence identity in the mature form.
FormulationLyophilized from a 0.2 μm filtered solution of 20mM PB, 500mM NaCl, pH 7.5.
ALTnamesC-C Motif Chemokine 27, CC Chemokine ILC, Cutaneous T-Cell-Attracting Chemokine, CTACK, Eskine, IL-11 R-Alpha-Locus Chemokine, Skinkine, Small-Inducible Cytokine A27, CCL27, ILC, SCYA27