Recombinant Human Brain Natriuretic Peptide/BNP (N-6His-Flag)
Recombinant Human Brain-type Natriuretic Peptide is produced by our E.coli expression system and the target gene encoding His27-Arg102 is expressed with a 6His, Flag tag at the N-terminus. Bon Opus Cat. #CM29
BackgroundBrain-type Natriuretic Peptide (BNP) is a nonglycosylated peptide that is produced predominantly by ventricular myocytes and belongs to the natriuretic peptide family. Proteolytic cleavage of the 12 kDa BNP precursor gives rise to N-terminal Pro BNP (NT-proBNP) and mature BNP. N-terminal proB-type natriuretic peptide (NT-proBNP), a useful marker of heart failure (HF), is considered to be secreted mainly from the ventricle, increased serum NT-proBNP levels are also encountered in conditions such as atrial fibrillation (AF) and atrial septal defect in patients without HF.
FormulationLyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
ALTnamesNatriuretic peptides B, Gamma-brain natriuretic peptide, NPPB, BNP