Recombinant Human Baculoviral IAP Repeat-Containing Protein 5/BIRC5/Survivin

SKU: CE87-10ug
$95.00Price
Recombinant Human BIRC5 is produced by our E.coli expression system and the target gene encoding Met1-Asp142 is expressed. Bon Opus Cat. #CE87
Size
  • Accession Number

    O15392
  • Background

    Baculoviral IAP Repeat-Containing Protein 5 (BIRC5) belongs to the IAP family. BIRC5 exists as a homodimer in the apo state and as a monomer in the CPC-bound state. BIRC5 contains one BIR repeat and is expressed only in fetal kidney and liver, and to lesser extent, lung and brain. BIRC5 functions as a multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. BIRC5 is also a component of a chromosome passage protein complex (CPC), which is essential for chromosome alignment and segregation during mitosis and cytokinesis. BIRC5 acts as an important regulator of the localization of this complex.
  • Expression

    E. coli
  • Packaging

    Ambient
  • Formulation

    Lyophilized from a 0.2 μm filtered solution of 20mM Tris, 0.1M NaCl, pH 7.5.
  • ALTnames

    Baculoviral IAP Repeat-Containing Protein 5, Apoptosis Inhibitor 4, Apoptosis Inhibitor Survivin, BIRC5, API4, IAP4

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