Recombinant Human Autophagy Related 4 Homolog C/ATG4C (C-6His)

Recombinant Human Autophagy Related 4 Homolog C/ATG4C (C-6His)

SKU: CE84-10ug
Recombinant Human Autophagy protein 4C is produced by our E.coli expression system and the target gene encoding Met1-Leu458 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #CE84
  • Accession Number

  • Background

    Cysteine Protease ATG4C (ATG4C) belongs to the peptidase C54 family. It is required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form which is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. ATG4C is a cytoplasmic protein and high expressed in skeletal muscle, liver, testis and heart. ATG4C can be inhibited by N-ethylmaleimide.
  • Expression

    E. coli
  • Packaging

    Dry ice/Polar packs
  • Formulation

    Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 100mM NaCl, 10% Glycerol, pH 8.0.
  • ALTnames

    Cysteine Protease ATG4C, AUT-Like 3 Cysteine Endopeptidase, Autophagin-3, Autophagy-Related Cysteine Endopeptidase 3, Autophagy-Related Protein 4 homolog C, ATG4C, APG4C, AUTL1, AUTL3
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