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Recombinant Human Aldo-Keto Reductase 1C4/AKR1C4 (N-6His)
Recombinant Human Aldo-Keto Reductase 1C4 is produced by our E.coli expression system and the target gene encoding Met1-Tyr323 is expressed with a 6His tag at the N-terminus. Bon Opus Cat. #CE36

Recombinant Human Aldo-Keto Reductase 1C4/AKR1C4 (N-6His)

SKU: CE36-10ug
$158.00Price
Quantity
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Phone: 800-943-6396 ext#1

Email: orders@bonopusbio.com

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Shipping Information

$48 Standard Overnight flat rate for products shipped in room temperature within the United States.

 

Additional $27 Ice Packs shipment fee is required for liquid proteins.

 

Please contact us to order for  international shipments.

Endotoxin
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Accession Number
P17516
Species
Human
Expression System
E.coli
Target Sequence
Met1-Tyr323
Tag
N-His
Formulation
Supplied as a 0.2 um filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Packaging
Dry ice/Polar packs
Background
Aldo-Keto Reductase 1C4/AKR1C4 is a member of the aldo/keto reductase family that consists of more than 40 known enzymes and proteins. AKR1C4 has highly expressed in Liver. It can catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. AKR1C4 catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-α-Androstan-3-α,17-β-diol (3-α-diol). In addition, AKR1C4 also has some 20-α-Hydroxysteroid Dehydrogenase activity.
Purity
Greater than 90% as determined by reducing SDS-PAGE.
Aldo-Keto Reductase Family 1 Member C4; 3-Alpha-HSD1; 3-Alpha-Hydroxysteroid Dehydrogenase Type I; Chlordecone Reductase; CDR; Dihydrodiol Dehydrogenase 4; DD-4; DD4; HAKRA; AKR1C4; CHDR
Alternative Names
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Citation
NA
Activity
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