Recombinant Human Aldo-Keto Reductase 1C3 is produced by our Mammalian expression system and the target gene encoding Met1-Tyr323 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #C985

Recombinant Human Aldo-Keto Reductase 1C3/AKR1C3 (C-6His)

Name: Recombinant Human Aldo-Keto Reductase 1C3/AKR1C3 (C-6His)
SKU: C985-10ug

SKU: C985-10ug

$158.00

Quantity

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Shipping Information

$48 Standard Overnight flat rate for products shipped in room temperature within the United States.

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Certificate of Analysis

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Endotoxin

Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.

Accession Number

P42330

Species

Human

Expression System

Human Cells

Target Sequence

Met1-Tyr323

C-His

Formulation

Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Packaging

Ambient

Background

AKR1C3, is an enzyme which belongs to the aldo/keto reductase family. It is expressed in many tissues including adrenal gland, brain, kidney, liver, lung, mammary gland, placenta, small intestine, colon, spleen, prostate and testis. AKR1C3 catalyzes the conversion of aldehydes and ketones to alcohols. It catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta-PGF2 to PGD2,which functions as a bi-directional 3-alpha-, 17-beta- and 20-alpha HSD. It can interconvert active androgens, estrogens and progestins with their cognate inactive metabolites.

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Aldo-Keto Reductase Family 1 Member C3; 17-Beta-Hydroxysteroid Dehydrogenase Type 5; 17-Beta-HSD 5; 3-Alpha-HSD Type II Brain; 3-Alpha-Hydroxysteroid Dehydrogenase Type 2; 3-Alpha-HSD Type 2; Chlordecone Reductase Homolog HAKRb; Dihydrodiol Dehydrogenase 3; DD-3; DD3; Dihydrodiol Dehydrogenase Type I; HA1753; Indanol Dehydrogenase; Prostaglandin F Synthase; Testosterone 17-Beta-Dehydrogenase 5; Trans-1;2-Dihydrobenzene-1;2-Diol Dehydrogenase; AKR1C3; DDH1; HSD17B5; KIAA0119; PGFS