Recombinant Human Alcohol Dehydrogenase Class 4 Mu/ADH7 (C-6His)
Recombinant Human ADH7 is produced by our Mammalian expression system and the target gene encoding Met1-Phe386 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #C882
BackgroundAlcohol dehydrogenase class 4 mu/sigma chain (ADH7) is a cytoplasm enzyme which is a member of the alcohol dehydrogenase family. The expression of this gene makes it much more abundant in the stomach than the liver, thus it differs from the other known gene family members. ADH7 may participate in the synthesis of retinoic acid, a hormone important for cellular differentiation. Medium-chain (octanol) and aromatic (m-nitrobenzaldehyde) compounds are the best substrates. Ethanol is not a good substrate but at the high ethanol concentrations reached in the digestive tract, it plays a role in the ethanol oxidation and contributes to the first pass ethanol metabolism.
FormulationLyophilized from a 0.2 μm filtered solution of PBS,PH7.4.
ALTnamesAlcohol Dehydrogenase Class 4 Mu/Sigma Chain, Alcohol Dehydrogenase Class IV Mu/Sigma Chain, Gastric Alcohol Dehydrogenase, Retinol Dehydrogenase, ADH7