Recombinant Human ACE-2 (C-Fc)

SKU: C05Y-10ug
$150.00Price
Recombinant Human Angiotensin-Converting Enzyme 2 is produced by our Mammalian expression system and the target gene encoding Gln18-Ser740 is expressed with a Fc tag at the C-terminus. DRA#C05Y
Size
  • Accession Number

    Q9BYF1
  • Purity

    Greater than 95% as determined by reducing SDS-PAGE.
  • Background

    Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don ’ t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.
  • Expression

    Human Cells
  • Packaging

    Dry ice/ice packs
  • ALTnames

    Angiotensin-Converting Enzyme 2; ACE-Related Carboxypeptidase; Angiotensin-Converting Enzyme Homolog; ACEH; Metalloprotease MPROT15; ACE2

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