Recombinant Human 4-1BB Ligand/4-1BBL/TNFSF9/CD137L (C-6His)
Recombinant Human 4-1BB ligand is produced by our E.coli expression system and the target gene encoding Arg71-Glu254 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #CH04
BackgroundTumor necrosis factor ligand superfamily member 9, also known as 4-1BBL, is a member of the the tumor necrosis factor family. It is a 254 amino acids cytokine that is expressed in brain, placenta, lung, skeletal muscle and kidney. TNFSF9 has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells, and is thought to be involved in T cell-tumor cell interaction.
FormulationLyophilized from a 0.2 μm filtered solution of 20mM PB，150mM NaCl,pH7.4.
ALTnamesTumor necrosis factor ligand superfamily member 9, 4-1BB ligand, 4-1BBL, TNFSF9.