Recombinant Human δ(3,5)-δ(2,4)-Dienoyl-CoA Isomerase, Mitochondrial/ECH1
Recombinant Human ECH1 is produced by our E.coli expression system and the target gene encoding Thr34-Leu328 is expressed with a 6His tag at the N-terminus. Bon Opus Cat. #CK08
BackgroundHuman delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase(ECH1) is a member of the hydratase/isomerase superfamily and contains a C-terminal peroxisomal targeting sequence and localizes to peroxisomes. ECH1 shows high sequence similarity to enoyl-CoA hydratases of several species, particularly within a conserved domain characteristic of these proteins. The rat orthologlocalizes to the matrix of both the peroxisome and mitochondria.It can isomerize 3-trans, 5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. ECH1 plays an important role in the auxiliary step of the fatty acid beta-oxidation pathway.
PackagingDry ice/Polar packs
FormulationSupplied as a 0.2 μm filtered solution of 20mM Tris,100mM NaCl,10% Glycerol,pH 8.0.
ALTnamesDelta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial,ECH1,, REF: C1008