Recombinant E. coli Tryptophan Synthase β Chain/Trp B

Recombinant E. coli Tryptophan Synthase β Chain/Trp B

SKU: CM31-10ug
$105.00Price
Recombinant E.coli Tryptophan synthase beta chain is produced by our E.coli expression system and the target gene encoding Thr2-Ile397 is expressed with a 6His tag at the N-terminus. Bon Opus Cat. #CM31
Size
  • Accession Number

    P0A879
  • Background

    Tryptophan synthase is an enzyme that catalyzes the final two steps in the biosynthesis of tryptophan. It is commonly found in Eubacteria, Archaebacteria, Protista, Fungi, and Plantae, but is absent from animals such as humans. Tryptophan synthase typically exists as an α-ββ-α complex.The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate: L-serine + 1-C-(indol-3-yl)glycerol 3-phosphate = L-tryptophan + D-glyceraldehyde 3-phosphate + H2O.The beta subunits catalyze the irreversible condensation of indole and serine to form tryptophan in a pyridoxal phosphate (PLP) dependent reaction. Their assembly into a complex leads to structural changes in both subunits resulting in reciprocal activation.
  • Expression

    E. coli
  • Packaging

    Ambient
  • Formulation

    Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
  • ALTnames

    Tryptophan synthase beta chain, trpB
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