Backgroundplatelet receptor Gi24 is a single-pass type I membrane protein, and located at the cell surface. The protein can be cleaved by MMP14, and stimulate MMP14-mediated MMP2 activation. It is participated in the BMP signaling pathway. It also regulates the CD4-pasitive, alpha-beta T cell proliferation, and T cell cytokine production negatively. However, the protein can regulate stem cell differentiation positively.
FormulationLyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
ALTnamesPlatelet receptor Gi24;Stress-induced secreted protein-1;Sisp-1;C10orf54;SISP1