Recombinant Cynomolgus Signal-regulatory Protein Beta-1 is produced by our Mammalian expression system and the target gene encoding Glu30-Pro369 is expressed with a 6His tag at the C-terminus.

Recombinant Cynomolgus SIRP beta 1(C-His)

Name: Recombinant Cynomolgus SIRP beta 1(C-His)
SKU: BP240-10ug
Price: 116 USD
Availability: InStock

SKU: BP240-10ug

$116.00

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Quantity

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Email: orders@bonopusbio.com

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Shipping Information

$48 Standard Overnight flat rate for products shipped in room temperature within the United States.

Additional $27 Ice Packs shipment fee is required for liquid proteins.

Please contact us to order for international shipments.

Certificate of Analysis

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Endotoxin

less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.

Accession Number

XP005568593.1

Species

Cynomolgus

Expression System

Human 293 Cells

Target Sequence

Glu30-Pro369

C-6His

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose.

Packaging

Ambient

Background

Signal-regulatory protein beta-1 is a type I membrane glycoprotein, that is is a member of the SIRP(CD172) family and also belongs to the immunoglobulin superfamily. Cynomolgus SIRP beta 1 shares 87% aa sequence identity with human SIRP beta 1. SIRP family members are are typically expressed in cells of monocyte, macrophage or dendritic lineages and are known to associate with the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK.