Recombinant Cynomolgus monkey CD47 molecule is produced by our Mammalian expression system and the target gene encoding Gln19-Pro139 is expressed with a Fc tag at the C-terminus. Bon Opus Cat. #CB76

Recombinant Cynomolgus CD47 molecule/CD47(C-Fc)

Name: Recombinant Cynomolgus CD47 molecule/CD47(C-Fc)
SKU: CB76-10ug

SKU: CB76-10ug

$110.00

Quantity

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Shipping Information

$48 Standard Overnight flat rate for products shipped in room temperature within the United States.

Additional $27 Ice Packs shipment fee is required for liquid proteins.

Please contact us to order for international shipments.

Certificate of Analysis

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Endotoxin

Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

Accession Number

F7A802

Species

Cynomolgus

Expression System

Human Cells

Target Sequence

Gln19-Pro139

C-Fc

Formulation

Lyophilized from a 0.2 um filtered solution of 50 mM Tris, 100 mM Glycine, pH7.5.

Packaging

Ambient

Background

CD47(Integrin-Associated Protein,IAP) is a 40 ‑ 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, and T cells. CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The protein is also a receptor for the C-terminal cell-binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This protein has broad tissue distribution, and is reduced in expression on Rh erythrocytes.