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Recombinant Cynomolgus monkey CD47 molecule is produced by our Mammalian expression system and the target gene encoding Gln19-Pro139 is expressed with a Fc tag at the C-terminus. Bon Opus Cat. #CB76

Recombinant Cynomolgus CD47 molecule/CD47(C-Fc)

SKU: CB76-10ug
$110.00Price
Quantity
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Endotoxin
Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Accession Number
F7A802
Species
Cynomolgus
Expression System
Human Cells
Target Sequence
Gln19-Pro139
Tag
C-Fc
Formulation
Lyophilized from a 0.2 um filtered solution of 50 mM Tris, 100 mM Glycine, pH7.5.
Packaging
Ambient
Background
CD47(Integrin-Associated Protein,IAP) is a 40 ‑ 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, and T cells. CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The protein is also a receptor for the C-terminal cell-binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This protein has broad tissue distribution, and is reduced in expression on Rh erythrocytes.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Leukocyte Surface Antigen CD47; Antigenic Surface Determinant Protein OA3; Integrin-Associated Protein; IAP; Protein MER6; CD47; MER6
Alternative Names
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Citation
NA
Activity
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