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Recombinant Cynomolgus CD47 molecule/CD47(C-Fc)

SKU: CB76-10ug
$105.00Price
Recombinant Cynomolgus monkey CD47 molecule is produced by our Mammalian expression system and the target gene encoding Gln19-Pro139 is expressed with a Fc tag at the C-terminus. Bon Opus Cat. #CB76
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  • Accession Number

    F7A802

  • Background

    CD47(Integrin-Associated Protein,IAP) is a 40-60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, and T cells. CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The protein is also a receptor for the C-terminal cell-binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This protein has broad tissue distribution, and is reduced in expression on Rh erythrocytes.

  • Expression

    Human Cells

  • Packaging

    Ambient

  • Formulation

    Lyophilized from a 0.2 μm filtered solution of 50 mM Tris, 100 mM Glycine, pH7.5.

  • ALTnames

    Leukocyte Surface Antigen CD47; Antigenic Surface Determinant Protein OA3; Integrin-Associated Protein; IAP; Protein MER6; CD47; MER6