Recombinant Cynomolgus B-cell maturation protein is produced by our Mammalian expression system andthe target gene encoding Met1-Ala53 is expressed with a 6His tag at the C-terminus.
Recombinant Cynomolgus BCMA (C-6His)
SKU: C01D-10ug
$80.00Price
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Shipping Information
$48 Standard Overnight flat rate for products shipped in room temperature within the United States.
Additional $27 Ice Packs shipment fee is required for liquid proteins.
Please contact us to order for international shipments.
Endotoxin
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Accession Number
G7Q0I4
Species
Cynomolgus
Expression System
Human Cells
Target Sequence
Met1-Ala53
Tag
C-6His
Formulation
Lyophilized from a 0.2 um filtered solution of 50 mM Tris-HCl, 100 mM Glycine, pH7.5.
Packaging
Ambient
Background
B cell maturation antigen (BCMA) is a member of the TNF receptor superfamily. It has been designated TNFRSF17. BCMA is a type III membrane protein containing one extracellular cysteine rich domain. Within the TNFRSF, it shares the highest homology with TACI. BCMA and TACI have both been shown to bind to APRIL and BAFF, members of the TNF ligand superfamily. BCMA expression has been found in immune organs and mature B cell lines. Although some expression has been observed at the cell surface, BCMA appears to be localized to the Golgi compartment. The binding of BCMA to APRIL or BAFF has been shown to stimulate IgM production in peripheral blood B cells and increase the survival of cultured B cells. This data suggests that BCMA may play an important role in B cell development,function and regulation.
Purity
Greater than 90% as determined by reducing SDS-PAGE.
Tumor necrosis factor receptor superfamily member 17; B-cell maturation protein; CD269; Tnfrsf17; Bcm; Bcma
Alternative Names
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Citation
NA
Activity
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