Recombinant Human Tripeptidyl-Peptidase I/TPP1 (C-6His)

SKU: CA36-10ug
Recombinant Human Tripeptidyl-Peptidase I is produced by our Mammalian expression system and the target gene encoding Ser20-Pro563 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #CA36
  • Accession Number

  • Background

    Tripeptidyl-Peptidase 1 (TPP1) belongs to the peptidase S53 family. TPP1 is detected in all tissues examined with highest levels in heart and placenta and relatively similar levels in other tissues. TPP1 is lysosomal serine protease with tripeptidyl-peptidase I activity. TPP1 may act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. TPP1 requires substrates with an unsubstituted N-terminus. TPP1 mutations have also been shown to cause neuronal ceroid lipofuscinosis type 2 (CLN2).
  • Expression

    Human Cells
  • Packaging

    Dry ice/ice packs
  • Formulation

    Supplied as a 0.2 μm filtered solution of 20mM TrisHCl,150mM NaCl,1mM GaCl2,10%Glycerol,pH7.5.
  • ALTnames

    Tripeptidyl-Peptidase 1, TPP-1, Cell Growth-Inhibiting Gene 1 Protein, Lysosomal Pepstatin-Insensitive Protease, LPIC, Tripeptidyl Aminopeptidase, Tripeptidyl-Peptidase I, TPP-I, TPP1, CLN2

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