Recombinant Human Toll-Interacting Protein/TOLLIP (C-6His)

Recombinant Human Toll-Interacting Protein/TOLLIP (C-6His)

SKU: CE59-10ug
$150.00Price
Recombinant Human Toll-Interacting Protein is produced by our E.coli expression system and the target gene encoding Ala2-Pro274 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #CE59
Size
  • Accession Number

    Q9H0E2
  • Background

    Toll-Interacting Protein (TOLLIP) is a member of the tollip family. TOLLIP localizes to the cytoplasm. It contains one C2 domain and one CUE domain. TOLLIP is an inhibitory adaptor protein for Toll-like receptors (TLR). The Toll-like receptors pathway is a part of the immune system that recognize structurally conserved molecular patterns of microbial pathogens, resulting in an inflammatory immune response. TOLLIP constitutes a complex with Tom1 to regulate endosomal transferring of ubiquitinated proteins. TOLLIP can negative regulate Toll-like receptors signaling, which may limit the production of proinflammatory mediators during the process of inflammation and infection.
  • Expression

    E.coli
  • Packaging

    Ambient
  • Formulation

    Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 5mM EDTA, pH 7.2.
  • ALTnames

    Toll-Interacting Protein, TOLLIP
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