Recombinant Human Syndecan-1/SDC1/CD138 (C-6His)
Recombinant Human Syndecan-1 is produced by our Mammalian expression system and the target gene encoding Gln23-Glu251 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #CA71
BackgroundSyndecan-1 is a single-pass type I membrane protein that belongs to the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. Human SDC1 is synthesized as a 310 amino acid precursor that contains a 22 amino acid signal sequence, and a 288 amino acid mature chain. The Syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered Syndecan-1 expression has been detected in several different tumor types.
FormulationLyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
ALTnamesSyndecan-1, SYND1, CD138, SDC1, SDC