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Recombinant Human Serpin Kazal-4/SPINK4 (C-6His)

Recombinant Human Serpin Kazal-4/SPINK4 (C-6His)

SKU: C543-10ug
$110.00Price
Recombinant Human SPINK4 is produced by our Mammalian expression system and the target gene encoding Gly27-Cys86 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #C543
Endotoxin
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Accession Number
O60575
Species
Human
Expression System
Human Cells
Target Sequence
Gly27-Cys86
Tag
C-His
Formulation
Lyophilized from a 0.2 um filtered solution of PBS, 1mM EDTA, 5% Mannitol, 7.4.
Packaging
Ambient
Background
Serine Protease Inhibitor Kazal-Type 4 (SPINK4) is a secreted protein containing one Kazal-like domain. SPINK4 is a member of the SPINK protein family. The gene family of serine protease inhibitors of the Kazal type (SPINK) are functional and positional candidate genes for celiac disease (CD). SPINK1 plays an important role in protecting the pancreas against excessive trypsinogen activation. It is a potent natural inhibitor of pancreatic trypsin activity. SPINK1 mutations are associated with the development of acute and chronic pancreatitis and have been detected in all forms of chronic pancreatitis. SPINK2 functions as a trypsin/acrosin inhibitor and is synthesized mainly in the testis and seminal vesicle where its activity is engaged in fertility. The SPINK2 protein contains a typical Kazal domain composed by six cysteine residues forming three disulfide bridges. SPINK9 was identified in human skin.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Serine Protease Inhibitor Kazal-Type 4; Peptide PEC-60 Homolog; SPINK4
Alternative Names
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Citation
NA
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