Recombinant Human Semaphorin 4D is produced by our Mammalian expression system and the target gene encoding Met22-Arg734 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #CC80

Recombinant Human Semaphorin-4D/SEMA4D/CD100 (C-6His)

Name: Recombinant Human Semaphorin-4D/SEMA4D/CD100 (C-6His)
SKU: CC80-10ug

SKU: CC80-10ug

$100.00

Quantity

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Shipping Information

$48 Standard Overnight flat rate for products shipped in room temperature within the United States.

Additional $27 Ice Packs shipment fee is required for liquid proteins.

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Certificate of Analysis

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Endotoxin

Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.

Accession Number

Q92854

Species

Human

Expression System

Human Cells

Target Sequence

Met22-Arg734

C-His

Formulation

Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Packaging

Ambient

Background

Semaphorin-4D is also known as A8,BB18, GR3, CD100. Semaphorin-4D belongs to the semaphorin family containing 1 Ig-like C2-type domain, 1 PSI domain and 1 Sema domain. It is the cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. It promotes the migration of cerebellar granule cells and of endothelial cells, regulates dendrite and axon branching and morphogenesis. Semaphorin-4D Plays a role in the immune system; Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade.