Recombinant Human pro-Nerve Growth Factor/pro-NGF (Glu19-Ala241)
SKU: C078-10ug
$105.00Price
Recombinant Human pro-Nerve Growth Factor is produced by our E.coli expression system and the target gene encoding Glu19-Ala241 is expressed. Bon Opus Cat. #C078
Size
Select
Accession Number
P01138Background
The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystin knot motif consisting of three cystine bridges, whereas proneurotrophins and mature neurotrophins elicit opposite biological effects. ProNGF functions preferentially via the complex of pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin inducing neuronal apoptosis and contributing to age- and disease-related neurodegeneration.Expression
E. coliPackaging
AmbientFormulation
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 250mM NaCl, pH 7.2.ALTnames
Beta-Nerve Growth Factor, Beta-NGF, NGF, NGFB, pro NGF
