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Recombinant Human/Mouse Activin A/INHBA
Recombinant Human Activin A is produced by our Mammalian expression system and the target gene encoding Gly311-Ser426 is expressed. Bon Opus Cat. #C687

Recombinant Human/Mouse Activin A/INHBA

SKU: C687-10ug
$158.00Price
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$48 Standard Overnight flat rate for products shipped in room temperature within the United States.

 

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Endotoxin
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Accession Number
P08476
Species
Human
Expression System
Human Cells
Target Sequence
Gly311-Ser426
Tag
tag free
Formulation
Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Packaging
Ambient
Background
Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Activins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins originally purified from gonadal fluids as proteins that stimulated pituitary follicle stimulating hormone (FSH) release. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Activins are homodimers or heterodimers of the various beta subunit isoforms, while inhibins are heterodimers of a unique alpha subunit and one of the various beta subunits.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Inhibin beta A chain;INHBA;Activin A
Alternative Names
Li, Q.V. et al. Genome-scale screens identify JNK–JUN signaling as a barrier for pluripotency exit and endoderm differentiation. Nature Genetics 51, 2019
Citation
Measured by its ability to induce SMAD signaling in 293-Activin A Res cells(Cat#XCC11).
Activity
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