Recombinant Human Growth differentiation factor 11 is produced by our Mammalian expression system and the target gene encoding Asn299-Ser407 is expressed. Bon Opus Cat. #C799

Recombinant Human Growth Dfferentiation Factor 11/GDF-11/BMP-11

Name: Recombinant Human Growth Dfferentiation Factor 11/GDF-11/BMP-11
SKU: C799-10ug

SKU: C799-10ug

$158.00

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Shipping Information

$48 Standard Overnight flat rate for products shipped in room temperature within the United States.

Additional $27 Ice Packs shipment fee is required for liquid proteins.

Please contact us to order for international shipments.

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Certificate of Analysis

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Endotoxin

Less than 1 EU/μg as determined by LAL test.

Accession Number

O95390

Species

Human

Expression System

Human Cells

Target Sequence

Asn299-Ser407

tag free

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 50% glycerol, pH 7.4.

Packaging

Ambient

Background

Growth/differentiation factor 11(GDF-11) is a secreted protein, which belongs to the transforming growth factor beta superfamily. GDF-11 controls anterior-posterior patterning by regulating the expression of Hox genes. The secreted signal acts globally to specify positional identity along the anterior/posterior axis during development. GDF11 has been shown to suppress neurogenesis through a pathway similar to that of myostatin, including stopping the progenitor cell-cycle during G-phase. The similarities between GDF11 and myostatin imply a likelihood that the same regulatory mechanisms are used to control tissue size during both muscular and neural development.