Recombinant Human EMMPRIN/Basigin/CD147 (C-6His)
Recombinant Human EMMPRIN is produced by our Mammalian expression system and the target gene encoding Ala22-His205 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #C433
BackgroundExtracellular Matrix Metalloproteinase Inducer (EMMPRIN) belongs to the immunoglobulin superfamily, which has the homology to both the immunoglobulin V domain and MHC class II antigen β-chain. EMMPRIN is a transmembrane glycoprotein with different forms, resulting from different modes of glycosylation and N-terminal sequence variants. EMMPRIN can be expressed in breast cancer, oral squamous cell carcinoma, glioma, lymphoma, lung, bladder, and melanoma carcinomas cells. EMMPRIN promotes invasion, metastasis, growth, and survival of malignants cells, serves as a receptor for extracellular cyclophilinthe, may play a role in signal transduction.
FormulationLyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
ALTnamesBasigin, 5F7, Collagenase Stimulatory Factor, Extracellular Matrix Metalloproteinase Inducer, EMMPRIN, Leukocyte Activation Antigen M6, OK Blood Group Antigen, Tumor Cell-Derived Collagenase Stimulatory Factor, TCSF, CD147, BSG