Recombinant Human Cystatin C/CST3 (N-6His)
Recombinant Human Cystatin C is produced by our E.coli expression system and the target gene encoding Gly26-Ala146 is expressed with a 6His tag at the N-terminus. Bon Opus Cat. #CE75
BackgroundCystatin C is a member of family 2 of the cystatin superfamily. It is ubiquitous in human tissues and body fluids and mainly used as a biomarker of kidney function. Cystatin C inhibits many cysteine proteases such as papain and Cathepsins B, H, K, L and S. As an inhibitor of cysteine proteinases, Cystatin C is thought to serve an important physiological role as a local regulator of this enzyme activity. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid (a specific type of protein deposition), such as Alzheimer's disease.
FormulationLyophilized from a 0.2 μm filtered solution of 20mM HEPES,150mM NaCl,pH7.4.
ALTnamesARMD11,Gamma-trace,Neuroendocrine basic polypeptide,Post-gamma-globulin,Cystatin-3