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Recombinant Human Complement Factor H-Related 1/CFHR1 (C-6His)
Recombinant Human CFHR1 is produced by our Mammalian expression system and the target gene encoding Glu19-Arg330 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #C585

Recombinant Human Complement Factor H-Related 1/CFHR1 (C-6His)

SKU: C585-10ug
$110.00Price
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Endotoxin
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Accession Number
Q03591
Species
Human
Expression System
Human Cells
Target Sequence
Glu19-Arg330
Tag
C-His
Formulation
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, 2mM EDTA, pH 7.4.
Packaging
Ambient
Background
Complement Factor H-Related 1 (CFHR1) is a 43 kDa secreted member of the factor H family of glycoproteins. The human Complement Factor H protein family consists of the complement and immune regulators factor H, the factor H-like protein 1 (FHL-1) and five factor H-related proteins (CFHR-1 to -5). Members of the H-related protein family are exclusively composed of individually folded protein domains, termed short consensus repeats (SCRs) or complement control modules. FHR1 is produced by hepatocytes and circulates as two differentially glycosylated isoforms (37 kDa and 43 kDa). Mature human FHR1 is 312 amino acids in length. It contains five, approximately 60 aa SCRs that basically constitute the entire molecule. FHR1 may play a role in complement regulation, lipid metabolism and lipoprotein complexes that bind PMNs to LPS.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Complement Factor H-Related Protein 1; FHR-1; H Factor-Like Protein 1; H-Factor-Like 1; H36; CFHR1; CFHL; CFHL1; CFHL1P; CFHR1P; FHR1; HFL1; HFL2
Alternative Names
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Citation
NA
Activity
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