Recombinant Human CNTF is produced by our E.coli expression system and the target gene encoding Ala2-Met200 is expressed. Bon Opus Cat. #C098
Recombinant Human Ciliary Neurotrophic Factor/CNTF
SKU: C098-10ug
$123.00Price
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Shipping Information
$48 Standard Overnight flat rate for products shipped in room temperature within the United States.
Additional $27 Ice Packs shipment fee is required for liquid proteins.
Please contact us to order for international shipments.
Endotoxin
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Accession Number
P26441
Species
Human
Expression System
E.coli
Target Sequence
Ala2-Met200
Tag
tag free
Formulation
Lyophilized from a 0.2 um filtered solution of 20mM TrisHCl, 100mM Nacl,ph8.0.
Packaging
Ambient
Background
Ciliary Neurotrophic Factor (CNTF) is a potent survival factor for neurons and oligodendrocytes. CNTF has also been shown to prevent the degeneration of motor axons after axotomy. CNTF is highly conserved across species and exhibits cross-species activities. Human and rat CNTF share approximately 83% homology in their protein sequence. CNTF is structurally related to IL6, IL11, LIF and OSM. All of these four helix bundle cytokines share gp130 as a signal transducing subunit in their receptor complexes. CNTF, like FGF acidic, FGF basic, and PD-ECGF (platelet-derived endothelial cell growth factor), does not possess a signal sequence that would allow secretion of the factor by classical secretion pathways. The mechanism underlying the release of CNTF is unknown.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Ciliary Neurotrophic Factor; CNTF
Alternative Names
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Citation
Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells.
Activity
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